Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25997240 | 0.80 | TERT (0.42) | KCNH2TERTDRD3DRD2LMNA | |
| SCHEMBL23249103 | 0.77 | HTR2C (0.44) | KCNH2DRD3DRD2KDM4ELMNA | |
| SCHEMBL17083424 | 0.75 | SMN1; SMN2 (0.47) | DRD3DRD2KDM4ELMNATP53 | |
| SCHEMBL24625580 | 0.72 | GRIN2B (0.34) | LMNATP53NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15470640 | 0.71 | HDAC4 (0.36) | DRD3DRD2LMNATP53NPC1 | |
| SCHEMBL2177816 | 0.71 | MCHR1 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL18798716 | 0.70 | NPC1 (0.33) | DRD3DRD2LMNATP53NPC1 | |
| SCHEMBL15069427 | 0.70 | HTT (0.40) | KCNH2TERTDRD3DRD2LMNA | |
| SCHEMBL15088679 | 0.70 | TERT (0.38) | KCNH2TERTDRD3DRD2LMNA | |
| SCHEMBL18914238 | 0.69 | HTR2C (0.49) | TERTDRD3DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219499-A1 | A CLASS OF FUSED RING COMPOUNDS, AND PREPARATION AND USE THEREOF | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |