SCHEMBL259982

SCHEMBL259982

[CH2]C(N)C(=O)Cc1ccsc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.46
SLC1A2 P43004 2/20 0.46
SLC1A1 P43005 2/20 0.46
TAAR1 Q96RJ0 1/20 0.41
POLB P06746 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
ALDH1A1 P00352 1/20 0.39
DPP4 P27487 1/20 0.39
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
GLS O94925 1/20 0.38
KMT2A Q03164 1/20 0.38
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12374111 0.85 SLC1A3 (0.49) SLC1A3SLC1A2SLC1A1TAAR1POLB
SCHEMBL9911542 0.78 ALDH1A1 (0.47) SLC1A3SLC1A2SLC1A1POLBNPC1
SCHEMBL11881891 0.76 ALDH1A1 (0.46) SLC1A3SLC1A2SLC1A1POLBNPC1
SCHEMBL1189465 0.75
SCHEMBL28023546 0.74 POLB (0.49) SLC1A3SLC1A2SLC1A1TAAR1POLB
Hydrochloric Acid SCHEMBL7117541 0.73 CA2 (0.47) SLC1A3SLC1A2SLC1A1TAAR1POLB
SCHEMBL6668571 0.73 TAAR1 (0.42) SLC1A3SLC1A2SLC1A1TAAR1POLB
SCHEMBL351615 0.72
SCHEMBL10624628 0.72
SCHEMBL19334011 0.72 CYP1A2 (0.43) SLC1A3SLC1A2SLC1A1POLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101346419-B Method for modifying insulating or semi-conductive surfaces, and resulting products ALCHIMER 2012-05-09 CN claimed
US-8133549-B2 Method for modifying insulating or semi-conductive surfaces, and resulting products ALCHIMER (FR) 2012-03-13 US claimed
EP-1948720-B1 USE OF A DIAZONIUM SALT IN A METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS ALCHIMER (FR) 2011-03-30 EP claimed
US-20090301862-A1 METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS ALCHIMEDICS (FR) 2009-12-10 US claimed
JP-2009518459-A 2009-05-07 JP claimed
CN-101346419-A Method for modifying insulating or semi-conductive surfaces, and resulting products ALCHIMER (FR) 2009-01-14 CN claimed
EP-1948720-A1 METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS Alchimer (FR) 2008-07-30 EP claimed
WO-2007048894-A1 METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS ALCHIMER (FR) 2007-05-03 WO claimed
CN-101346419-B Method for modifying insulating or semi-conductive surfaces, and resulting products ALCHIMER 2012-05-09 CN disclosed
US-8133549-B2 Method for modifying insulating or semi-conductive surfaces, and resulting products ALCHIMER (FR) 2012-03-13 US disclosed
EP-1948720-B1 USE OF A DIAZONIUM SALT IN A METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS ALCHIMER (FR) 2011-03-30 EP disclosed
US-20090301862-A1 METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS ALCHIMEDICS (FR) 2009-12-10 US disclosed
CN-101346419-A Method for modifying insulating or semi-conductive surfaces, and resulting products ALCHIMER (FR) 2009-01-14 CN disclosed
EP-1948720-A1 METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS Alchimer (FR) 2008-07-30 EP disclosed
WO-2007048894-A1 METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS ALCHIMER (FR) 2007-05-03 WO disclosed