Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600372 | 0.92 | LMNA (0.36) | USP2LMNAAGTR1CYP1A2KDM4E | |
| SCHEMBL1062613 | 0.76 | — | — | |
| SCHEMBL8386335 | 0.75 | USP2 (0.39) | USP2LMNAAGTR1CYP1A2KDM4E | |
| SCHEMBL28130472 | 0.73 | — | — | |
| SCHEMBL10818291 | 0.73 | LMNA (0.37) | USP2LMNAAGTR1CYP1A2KDM4E | |
| SCHEMBL6240929 | 0.72 | LMNA (0.40) | USP2LMNAAGTR1CYP1A2KDM4E | |
| SCHEMBL312702 | 0.71 | — | — | |
| SCHEMBL30443539 | 0.70 | LMNA (0.38) | USP2LMNAAGTR1CYP1A2KDM4E | |
| SCHEMBL810887 | 0.69 | — | — | |
| SCHEMBL13416103 | 0.68 | LMNA (0.34) | USP2LMNAAGTR1CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158740-B2 | Hydrophilic silicones | ONE UNLIMITED, INC. (US) | 2012-04-17 | — | — | US | disclosed |