Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984836 | 0.88 | LMNA (0.44) | USP2LMNAKDM4EDUSP3MEN1 | |
| SCHEMBL10818291 | 0.79 | LMNA (0.37) | USP2LMNAKDM4EDUSP3MEN1 | |
| Propylene Glycol SCHEMBL9630641 | 0.78 | TDP1 (0.53) | ALDH1A1TSHR | |
| Propylene Glycol SCHEMBL22320908 | 0.78 | TDP1 (0.53) | ALDH1A1TSHR | |
| SCHEMBL14719495 | 0.75 | TSHR (0.35) | KDM4ETSHR | |
| SCHEMBL2600370 | 0.75 | USP2 (0.35) | USP2LMNAKDM4EDUSP3MEN1 | |
| Isopropyl Alcohol SCHEMBL28165739 | 0.75 | LMNA (0.38) | LMNAALDH1A1TSHR | |
| Isopropyl Alcohol SCHEMBL28183520 | 0.75 | LMNA (0.38) | LMNAALDH1A1TSHR | |
| Alcohol SCHEMBL442255 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TSHR | |
| SCHEMBL13416103 | 0.74 | LMNA (0.34) | USP2LMNAKDM4EDUSP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104212409-B | The main binding agent being made up of polyorganosiloxane compounds | 琳得科株式会社 | 2016-08-24 | — | — | CN | disclosed |
| US-5891914-A | COMPLEX OF ORGANOSILICON COMPOUND AND ACTIVE MATERIALS | SPECIAL ADVANCED BIOMATERIALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |
| US-5686065-A | Topical siloxane sunscreen compositions having enhanced performance and safety | SPECIAL ADVANCED BIOMATERIALS, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1992017184-A2 | BIOACTIVE TOPICAL SILOXANE COMPOSITIONS HAVING ENHANCED PERFORMANCE AND SAFETY | SPECIAL ADVANCED BIOMATERIALS, INC. (US) | 1992-10-15 | — | — | WO | disclosed |