Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | SHBG | P04278 | 2/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.64 |
| ▸ | SNCA | P37840 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42713 | 1.00 | CYP19A1 (1.00) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL42712 | 1.00 | CYP19A1 (1.00) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL3275185 | 0.87 | CYP19A1 (0.78) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL7097095 | 0.87 | CYP19A1 (0.78) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL6821320 | 0.87 | CYP19A1 (0.78) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL349057 | 0.86 | CYP19A1 (0.76) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL349056 | 0.86 | CYP19A1 (0.76) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL10187417 | 0.86 | CYP19A1 (0.76) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL7649810 | 0.86 | CYP19A1 (0.75) | CYP19A1 | |
| SCHEMBL10528769 | 0.84 | CYP19A1 (1.00) | CYP19A1ALDH1A1LMNASHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163944-B2 | Allylic oxidations catalyzed by dirhodium catalysts under aqueous conditions | UNIVERSITY OF MARYLAND COLLEGE PARK (US) | 2012-04-24 | — | — | US | disclosed |
| US-8163944-B2 | Allylic oxidations catalyzed by dirhodium catalysts under aqueous conditions | UNIVERSITY OF MARYLAND COLLEGE PARK (US) | 2012-04-24 | — | — | US | disclosed |
| US-20090093638-A1 | Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093638-A1 | Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093638-A1 | Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions | CYP11B2, DHCR7, ZDHHC7 | CYP19A1 130/4885ALDH1A1 530/4885LMNA 4340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.