Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27973717 | 1.00 | POLB (0.55) | POLBALDH1A1HPGDCHRM2CHRM4 | |
| SCHEMBL8667174 | 1.00 | POLB (0.55) | POLBALDH1A1HPGDCHRM2CHRM4 | |
| SCHEMBL11827575 | 0.88 | ALDH1A1 (0.52) | ALDH1A1HPGDCYP19A1PTPN2PTPN1 | |
| SCHEMBL23566376 | 0.86 | MEN1 (0.54) | POLBALDH1A1HPGDCYP19A1KDM4E | |
| SCHEMBL18640744 | 0.86 | MEN1 (0.54) | POLBALDH1A1HPGDCYP19A1KDM4E | |
| SCHEMBL9493633 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP19A1KDM4ENPSR1 | |
| SCHEMBL12898142 | 0.84 | POLB (0.55) | POLBALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL1862739 | 0.84 | ALDH1A1 (0.60) | ALDH1A1HPGDCYP19A1KDM4ENPSR1 | |
| SCHEMBL10672814 | 0.83 | ALDH1A1 (0.66) | ALDH1A1HPGDCYP19A1KDM4ENPSR1 | |
| SCHEMBL31307177 | 0.83 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP19A1PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067440-B2 | Phosphonium salts derivatives and uses thereof | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-11-29 | — | — | US | disclosed |
| US-7947816-B2 | Azodicarboxylic acid bis(2-alkoxyethyl) ester compound, and production intermediate thereof | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2011-05-24 | — | — | US | disclosed |
| US-7947816-B2 | Azodicarboxylic acid bis(2-alkoxyethyl) ester compound, and production intermediate thereof | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2011-05-24 | — | — | US | disclosed |
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-04-21 | — | — | US | disclosed |
| US-20110028701-A1 | AZODICARBOXYLIC ACID BIS(2-ALKOXYETHYL) ESTER COMPOUND, AND PRODUCTION INTERMEDIATE THEREOF | TOYOBO MC CORPORATION (JP) | 2011-02-03 | — | — | US | disclosed |
| US-20110028701-A1 | AZODICARBOXYLIC ACID BIS(2-ALKOXYETHYL) ESTER COMPOUND, AND PRODUCTION INTERMEDIATE THEREOF | TOYOBO MC CORPORATION (JP) | 2011-02-03 | — | — | US | disclosed |
| US-7880037-B2 | Phosphonium supported triphenylphosphine; for controlling solubility of a molecule; oxidation of Cinnamyl Alcohol using above catalyst system | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-02-01 | — | — | US | disclosed |
| US-7820802-B2 | Azodicarboxylic acid bis(2-alkoxyethyl) ester compound, and production intermediate thereof | TOYOBO MC CORPORATION (JP) | 2010-10-26 | — | — | US | disclosed |
| US-7820802-B2 | Azodicarboxylic acid bis(2-alkoxyethyl) ester compound, and production intermediate thereof | TOYOBO MC CORPORATION (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20100048881-A1 | AZODICARBOXYLIC ACID BIS(2-ALKOXYETHYL) ESTER COMPOUND, AND PRODUCTION INTERMEDIATE THEREOF | TOYO KASEI KOGYO CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20100048881-A1 | AZODICARBOXYLIC ACID BIS(2-ALKOXYETHYL) ESTER COMPOUND, AND PRODUCTION INTERMEDIATE THEREOF | TOYO KASEI KOGYO CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2112136-A1 | BIS(2-ALKOXYETHYL) AZODICARBOXYLATE ESTER COMPOUND AND INTERMEDIATE FOR PRODUCTION OF THE SAME | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2009-10-28 | — | — | EP | disclosed |
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | VALORISATION-RECHERECHE (CA) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028701-A1 | AZODICARBOXYLIC ACID BIS(2-ALKOXYETHYL) ESTER COMPOUND, AND PRODUCTION INTERMEDIATE THEREOF | CPS1, MCCC2, PC | POLB 127/4885ALDH1A1 554/4885HPGD 1557/4885 |
| US-20070197477-A1 | PHOSPHONIUM SALTS DERIVATIVES | PI4K2A, PIP4K2A, PI4K2B | POLB 1291/4885ALDH1A1 3806/4885HPGD 3362/4885 |
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | PI4K2A, PIP4K2A, PI4K2B | POLB 1264/4885ALDH1A1 3468/4885HPGD 2667/4885 |
| US-20100048881-A1 | AZODICARBOXYLIC ACID BIS(2-ALKOXYETHYL) ESTER COMPOUND, AND PRODUCTION INTERMEDIATE THEREOF | CPS1, MCCC2, PC | POLB 127/4885ALDH1A1 554/4885HPGD 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.