SCHEMBL26005369

SCHEMBL26005369

CN(N)CCNCCNC1CCN(C)CC1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MITF O75030 1/20 0.36
DPP7 Q9UHL4 1/20 0.35
NCF1 P14598 1/20 0.33
POLB P06746 1/20 0.33
OPRL1 P41146 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14980285 0.80 MEN1 (0.40) MEN1KMT2AMITFDPP7NCF1
SCHEMBL24204325 0.80 TDP1 (0.43) MEN1KMT2AMITFDPP7OPRL1
Hydrochloric Acid SCHEMBL4651637 0.79 MEN1 (0.39) MEN1KMT2AMITFDPP7NCF1
SCHEMBL24801582 0.79 ACE2 (0.45) MEN1KMT2AMITFDPP7NCF1
SCHEMBL24204664 0.78 MEN1 (0.47) MEN1KMT2AMITFDPP7NCF1
SCHEMBL24204306 0.77 ACE2 (0.44) MEN1KMT2AMITFDPP7POLB
SCHEMBL24802107 0.76 CASP2 (0.46) MEN1KMT2AMITFDPP7NCF1
SCHEMBL24802282 0.75 DPP7 (0.41) MEN1KMT2AMITFDPP7NCF1
SCHEMBL24204571 0.75 CYP2C9 (0.42) POLB
SCHEMBL24802105 0.75 SQLE (0.46) MEN1KMT2AMITFDPP7NCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022268052-A9 (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE BEIGENE, LTD. (KY) 2023-08-17 WO disclosed