Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 2/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25357301 | 0.92 | KDM4E (0.50) | KDM4ESLC7A5NOS3NOS1NOS2 | |
| SCHEMBL26009753 | 0.92 | KDM4E (0.50) | KDM4ESLC7A5NOS3NOS1NOS2 | |
| SCHEMBL26008256 | 0.89 | KDM4E (0.53) | KDM4ESLC7A5NOS3NOS1TPSAB1 | |
| SCHEMBL26009187 | 0.89 | KDM4E (0.53) | KDM4ESLC7A5NOS3NOS1TPSAB1 | |
| SCHEMBL26008244 | 0.81 | KDM4E (0.51) | KDM4ESLC7A5NOS3NOS1TPSAB1 | |
| SCHEMBL26009757 | 0.81 | KDM4E (0.51) | KDM4ESLC7A5NOS3NOS1TPSAB1 | |
| SCHEMBL25356954 | 0.81 | KDM4E (0.51) | KDM4ESLC7A5NOS3NOS1TPSAB1 | |
| SCHEMBL26008156 | 0.76 | KMT2A (0.40) | KDM4EPKM | |
| SCHEMBL26008260 | 0.76 | ITGB3 (0.48) | SLC7A5HRH3ALDH1A1 | |
| SCHEMBL31688766 | 0.73 | SLC7A5 (0.65) | KDM4ESLC7A5NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | KDM4E 4463/4885SLC7A5 21/4885NOS3 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.