SCHEMBL26014235

SCHEMBL26014235

OB(O)c1cc2c(cc1Br)C(c1cccc(-c3ccccc3)c1)(c1cccc(-c3ccccc3)c1)c1ccccc1-2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
MGLL Q99685 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PDK2 Q15119 7/20 0.35
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HSP90AA1 P07900 1/20 0.32
COMT P21964 1/20 0.31
UTS2R Q9UKP6 1/20 0.31
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30
BACE1 P56817 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24730434 0.85 MEN1 (0.41) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL26014214 0.84 ESR1 (0.38) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL15966167 0.79 ESR1 (0.47) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL28500082 0.78 MEN1 (0.50) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL16922972 0.77 PDK2 (0.44) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL28610052 0.76 PDK2 (0.43) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL26024343 0.76 KDM4E (0.33) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL6438074 0.74 PDK2 (0.45) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL26157461 0.74 ALDH1A1 (0.39) ESR1ESR2KDM4EMEN1LMNA
SCHEMBL16858246 0.74 PDK2 (0.44) ESR1ESR2KDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-21 US disclosed
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-09-21 US disclosed
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-17 US disclosed
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230301184-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS THEREOF OCIAD1, OCIAD2, OSTC ESR1 70/4885ESR2 171/4885MGLL 786/4885
US-20230257387-A1 ORGANIC COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF OCIAD1, OCIAD2, EPCAM ESR1 6/4885ESR2 41/4885MGLL 632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.