SCHEMBL2601430

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15143486	0.81	PIM1 (0.42)	PIM1USP8USP7MAOBMIF
	SCHEMBL12998131	0.78	MIF (0.42)	MAOBMIFTDP1MEN1KMT2A
	SCHEMBL18796296	0.78	MAOB (0.49)	PIM1MAOBMIFTDP1MEN1
	SCHEMBL22261555	0.78	MIF (0.42)	PIM1MAOBMIFTDP1MEN1
	SCHEMBL2601487	0.78	MIF (0.42)	PIM1MAOBMIFTDP1MEN1
	SCHEMBL10446873	0.78	MIF (0.42)	PIM1MAOBMIFTDP1MEN1
	SCHEMBL21183649	0.78	MIF (0.42)	PIM1MAOBMIFTDP1MEN1
	SCHEMBL10446552	0.75	MIF (0.43)	PIM1MAOBMIFTDP1MEN1
	SCHEMBL2601428	0.74	ALDH1A1 (0.49)	MAOBMIFTDP1MEN1KMT2A
	SCHEMBL20924695	0.72	MAOB (0.43)	PIM1MAOBMIFTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.