Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171441 | 0.86 | ALDH1A1 (0.52) | TAAR1ALDH1A1SLC6A4TSHR | |
| SCHEMBL23343767 | 0.85 | CYP4F2 (0.40) | MAOBTAAR1CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL17449712 | 0.83 | FFAR4 (0.40) | MAOBCYP4F2CYP4A11MAOAALDH1A1 | |
| SCHEMBL2623872 | 0.81 | IDO1 (0.41) | MAOBMAOATSHR | |
| SCHEMBL31462949 | 0.80 | FFAR4 (0.37) | CYP4F2CYP4A11SLC6A4FFAR4 | |
| SCHEMBL24180116 | 0.80 | FFAR4 (0.37) | CYP4F2CYP4A11SLC6A4FFAR4 | |
| SCHEMBL17449728 | 0.79 | FFAR4 (0.41) | CYP4F2CYP4A11FFAR4 | |
| SCHEMBL22861116 | 0.78 | TAAR1 (0.42) | MAOBTAAR1MAOAALDH1A1SLC6A4 | |
| SCHEMBL15267204 | 0.78 | TACR1 (0.45) | MAOBTAAR1MAOAALDH1A1SLC6A4 | |
| SCHEMBL241171 | 0.78 | PTGS2 (0.43) | MAOBTAAR1CYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154291-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-08-17 | — | — | WO | disclosed |