Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PPM1D | O15297 | 1/20 | 0.31 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26015098 | 0.77 | CHRM3 (0.30) | TOP2ACHRM3 | |
| SCHEMBL6399788 | 0.73 | OPRM1 (0.39) | TOP2ASLC6A3CHRM3 | |
| SCHEMBL26015241 | 0.70 | CHRM3 (0.30) | TOP2ACHRM3PPM1D | |
| SCHEMBL26015101 | 0.70 | CHRM3 (0.30) | TOP2ACHRM3PPM1D | |
| SCHEMBL6400406 | 0.69 | OPRL1 (0.40) | PPM1D | |
| SCHEMBL29130336 | 0.65 | MAPK1 (0.37) | PPM1D | |
| SCHEMBL22375300 | 0.65 | GAA (0.35) | PPM1D | |
| SCHEMBL22375302 | 0.65 | GAA (0.35) | PPM1D | |
| SCHEMBL16746019 | 0.65 | GAA (0.35) | PPM1D | |
| SCHEMBL22375299 | 0.65 | GAA (0.35) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11732001-B2 | Methods of incorporating an amino acid comprising a BCN group into a polypeptide using an orthogonal codon encoding it and an orthogonal pylrs synthase | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11732001-B2 | Methods of incorporating an amino acid comprising a BCN group into a polypeptide using an orthogonal codon encoding it and an orthogonal pylrs synthase | COASY, BCAT1, FARSA | TOP2A 3802/4885NR5A2 4685/4885SLC6A3 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.