SCHEMBL2601600

SCHEMBL2601600

O=[N+]([O-])c1cc(-c2ccccc2)ccc1Br

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.58
CRHR2 Q13324 1/20 0.58
ALDH1A1 P00352 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
MAPT P10636 2/20 0.48
POLB P06746 2/20 0.48
ABCB1 P08183 6/20 0.47
ABCC1 P33527 5/20 0.47
KCNMA1 Q12791 1/20 0.47
CYP2D6 P10635 1/20 0.46
CTSB P07858 1/20 0.45
MAPK1 P28482 2/20 0.43
KDM4E B2RXH2 1/20 0.43
LMNA P02545 1/20 0.43
HPGD P15428 1/20 0.43
HSP90AA1 P07900 1/20 0.43
HPRT1 P00492 1/20 0.42
ACLY P53396 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12566736 0.87 MAPT (0.50) CRHBPCRHR2ALDH1A1MEN1KMT2A
SCHEMBL30145522 0.85 CRHBP (0.53) CRHBPCRHR2ALDH1A1MEN1KMT2A
SCHEMBL14928247 0.85 CRHBP (0.53) CRHBPCRHR2ALDH1A1MEN1KMT2A
SCHEMBL1663325 0.82 CRHBP (0.63) CRHBPCRHR2ALDH1A1MEN1KMT2A
SCHEMBL9251940 0.82 CA1 (0.47) CRHBPCRHR2ALDH1A1MEN1KMT2A
SCHEMBL10947339 0.82 MAPT (0.48) ALDH1A1MEN1KMT2ATDP1MAPT
SCHEMBL2816974 0.81 CRHBP (0.61) CRHBPCRHR2ALDH1A1MEN1KMT2A
SCHEMBL14951414 0.81 CRHBP (0.57) CRHBPCRHR2ALDH1A1MEN1KMT2A
SCHEMBL28868112 0.80 CRHBP (0.61) CRHBPCRHR2ALDH1A1MEN1KMT2A
SCHEMBL28122064 0.80 ALDH1A1 (0.56) CRHBPCRHR2ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2448035-B1 Organic light-emitting device SAMSUNG DISPLAY CO LTD (KR) 2014-06-11 EP disclosed
US-8546793-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2013-10-01 US disclosed
US-8546793-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2013-10-01 US disclosed
CN-103183691-A 6-mesitylene-6H-6-boron hetero benzo[cd]pyrene derivative containing substituted or non-substituted carbazolyl, and preparation method and application thereof, and luminescent device comprising same KUNSHAN VISIONOX DISPLAY TECH 2013-07-03 CN disclosed
US-8455867-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2013-06-04 US disclosed
US-8455867-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2013-06-04 US disclosed
WO-2013069939-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT INCLUDING THE SAME, ELECTRONIC DEVICE THEREOF 덕산하이메탈(주) (KR) 2013-05-16 WO disclosed
WO-2013069939-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT INCLUDING THE SAME, ELECTRONIC DEVICE THEREOF 덕산하이메탈(주) (KR) 2013-05-16 WO disclosed
US-8431251-B2 Heterocyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2013-04-30 US disclosed
US-8405074-B2 2013-03-26 US disclosed
US-4652658-A Process for making 2-oxindole-1-carboxamides and intermediates therefor PFIZER INC. (US) 1987-03-24 US disclosed
CN-85103527-A Preparation N, the method for the disubstituted 2-hydroxyindole of 3--1-hydroxyalkyl cooh amide 1987-01-28 CN disclosed
CN-85101029-A The method of preparation-2-oxyindole-1-methane amide and intermediate product thereof 1987-01-24 CN disclosed
US-4569942-A N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents PFIZER INC. (US) 1986-02-11 US disclosed
EP-0164860-A1 N,3-disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents PFIZER INC. (US) 1985-12-18 EP disclosed
US-4556672-A 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents PFIZER INC. (US) 1985-12-03 US disclosed
EP-0156603-A2 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents PFIZER INC. (US) 1985-10-02 EP disclosed
EP-0155828-A2 Process for making 2-oxindole-1-carboxamides and intermediates therefor PFIZER INC. (US) 1985-09-25 EP disclosed
EP-0153818-A2 1,3-Disubstituted 2-oxindoles as analgesic and anti-inflammatory agents PFIZER INC. (US) 1985-09-04 EP disclosed
US-4259475-A FRIEDEL-CRAFTS COMPLEX CATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1981-03-31 US disclosed