Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239368 | 1.00 | MAPK1 (0.35) | MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL15813670 | 1.00 | MAPK1 (0.35) | MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL20250956 | 1.00 | MAPK1 (0.35) | MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL20250955 | 1.00 | MAPK1 (0.35) | MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL16017770 | 1.00 | MAPK1 (0.35) | MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL1476894 | 1.00 | MAPK1 (0.35) | MAPK1ALDH1A1MEN1KMT2A | |
| Water SCHEMBL9448565 | 0.97 | MAPK1 (0.33) | MAPK1ALDH1A1MEN1KMT2A | |
| Ethylene SCHEMBL3275731 | 0.94 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL237181 | 0.89 | MAPK1 (0.40) | MAPK1ALDH1A1 | |
| SCHEMBL20436939 | 0.88 | CYP4F2 (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11707452-B2 | Modulators of alpha-synuclein proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11707452-B2 | Modulators of alpha-synuclein proteolysis and associated methods of use | UCHL1, ADRM1, CRBN | MAPK1 4023/4885ALDH1A1 2567/4885MEN1 3483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.