Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24349310 | 0.95 | KDM4E (0.43) | APEX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL26017482 | 0.91 | APEX1 (0.49) | APEX1KDM4EALDH1A1RPS6KB2MAPT | |
| SCHEMBL26016604 | 0.91 | KDM4E (0.40) | APEX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24349531 | 0.91 | KDM4E (0.41) | APEX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24349307 | 0.91 | APEX1 (0.60) | APEX1KDM4EHDAC6L3MBTL1ALDH1A1 | |
| SCHEMBL26017384 | 0.89 | APEX1 (0.48) | APEX1KDM4EALDH1A1HSD17B10MAPK8 | |
| SCHEMBL26017481 | 0.86 | APEX1 (0.41) | APEX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL26016607 | 0.86 | KDM4E (0.37) | APEX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24349537 | 0.86 | APEX1 (0.57) | APEX1KDM4EHDAC6L3MBTL1ALDH1A1 | |
| SCHEMBL26016602 | 0.85 | APEX1 (0.46) | APEX1KDM4EHDAC6L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265058-A1 | CARBOXYLIC ACID OR CARBOXYLIC ACID ESTER COMPOUND HAVING FUSED-RING STRUCTURE, METHOD FOR PRODUCING THE SAME, AND USE OF COMPOUND | FUJIFILM CORPORATION (JP) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265058-A1 | CARBOXYLIC ACID OR CARBOXYLIC ACID ESTER COMPOUND HAVING FUSED-RING STRUCTURE, METHOD FOR PRODUCING THE SAME, AND USE OF COMPOUND | SPG11, HAT1, ASS1 | APEX1 2815/4885KDM4E 4186/4885HDAC6 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.