Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26837235 | 0.81 | DRD2 (0.39) | MAPTNPC1ALDH1A1RAB9ADRD2 | |
| SCHEMBL26837612 | 0.75 | HRH4 (0.41) | MAPKAPK2TDP1MAPTKDM4ENPC1 | |
| SCHEMBL29736188 | 0.74 | MAPKAPK2 (0.54) | MAPKAPK2TDP1MAPTKDM4EALDH1A1 | |
| SCHEMBL26675972 | 0.74 | MAPKAPK2 (0.54) | MAPKAPK2TDP1MAPTKDM4EALDH1A1 | |
| SCHEMBL26837357 | 0.72 | KDM4E (0.52) | MAPKAPK2TDP1MAPTKDM4EALDH1A1 | |
| SCHEMBL26017358 | 0.67 | DRD1 (0.48) | MAPKAPK2CDK1TDP1MAPTKDM4E | |
| SCHEMBL25429947 | 0.67 | MAPKAPK2 (0.56) | MAPKAPK2TDP1MAPTKDM4EALDH1A1 | |
| SCHEMBL31596344 | 0.67 | MAPKAPK2 (0.56) | MAPKAPK2TDP1MAPTKDM4EALDH1A1 | |
| SCHEMBL19630774 | 0.66 | SLC6A4 (0.50) | MAPKAPK2CDK1 | |
| SCHEMBL19630773 | 0.66 | SLC6A4 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122135-A1 | SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME | KULEON LLC (US) | 2023-06-29 | — | — | WO | disclosed |