Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 16/20 | 0.43 |
| ▸ | PARP1 | P09874 | 16/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 16/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26018420 | 0.80 | HPRT1 (0.36) | TNKSPARP1TNKS2KDM4EALDH1A1 | |
| SCHEMBL8499455 | 0.70 | ALDH1A1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL8485777 | 0.70 | CYP2C19 (0.39) | ALDH1A1 | |
| SCHEMBL20954788 | 0.69 | TNKS (0.51) | TNKSPARP1TNKS2 | |
| SCHEMBL26018017 | 0.69 | TNKS (0.48) | TNKSPARP1TNKS2 | |
| SCHEMBL9184240 | 0.68 | PARP1 (0.51) | TNKSPARP1TNKS2KDM4EALDH1A1 | |
| SCHEMBL2624085 | 0.67 | TSHR (0.49) | TNKSPARP1TNKS2KDM4EALDH1A1 | |
| SCHEMBL3542410 | 0.67 | NPSR1 (0.49) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL13081092 | 0.67 | HTR2A (0.46) | TNKSPARP1TNKS2KDM4EALDH1A1 | |
| SCHEMBL15468376 | 0.67 | ALDH1A1 (0.39) | PARP1ALDH1A1HPGDCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |