Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | INMT | O95050 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26017983 | 0.80 | TNKS (0.43) | NPSR1CHEK1TSHRHTTKMT2A | |
| SCHEMBL20954967 | 0.72 | POLB (0.40) | HPGDINMTPOLBTNKSPARP1 | |
| SCHEMBL26018436 | 0.72 | POLB (0.40) | HPGDINMTPOLBTNKSPARP1 | |
| SCHEMBL22214072 | 0.67 | GRIA1 (0.39) | HTTHPGDGAAPOLBKDM4E | |
| SCHEMBL2624085 | 0.64 | TSHR (0.49) | NPSR1CHEK1TSHRHTTKMT2A | |
| SCHEMBL3542410 | 0.64 | NPSR1 (0.49) | NPSR1CHEK1TSHRHTTKMT2A | |
| SCHEMBL12349970 | 0.63 | GAA (0.50) | NPSR1CHEK1TSHRHTTKMT2A | |
| SCHEMBL13911357 | 0.63 | GAA (0.50) | NPSR1CHEK1TSHRHTTKMT2A | |
| SCHEMBL6673121 | 0.62 | GDA (0.36) | HPRT1PDE4AADORA2APDE4BPDE4C | |
| SCHEMBL18635 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |