SCHEMBL260180

SCHEMBL260180

C[N+](C)(C)CCOP(=O)(O)OCCCC=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.43
LMNA P02545 2/20 0.42
AKT1 P31749 2/20 0.42
ADRA1A P35348 2/20 0.42
ESR1 P03372 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
CDC25A P30304 1/20 0.42
AGTR1 P30556 1/20 0.42
KCNH2 Q12809 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
LPAR3 Q9UBY5 4/20 0.38
BBOX1 O75936 2/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
S1PR1 P21453 1/20 0.36
PRKD3 O94806 1/20 0.34
PRKCG P05129 1/20 0.34
PRKCB P05771 1/20 0.34
PRKCA P17252 1/20 0.34
PRKCH P24723 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29128926 0.85 LPAR3 (0.50) FABP3LMNAAKT1ADRA1AESR1
SCHEMBL17833014 0.83 LMNA (0.58) FABP3LMNAAKT1ADRA1AESR1
SCHEMBL13619237 0.83 LMNA (0.58) FABP3LMNAAKT1ADRA1AESR1
SCHEMBL25857265 0.83 SMN1; SMN2 (0.46) FABP3LMNAAKT1ADRA1AESR1
SCHEMBL29539933 0.83 LMNA (0.63) LMNAAKT1ADRA1AESR1ADORA3
SCHEMBL100728 0.82 FABP3 (0.39) FABP3LMNAAKT1ADRA1AESR1
SCHEMBL25058831 0.80 LMNA (0.46) FABP3LMNAAKT1ADRA1AESR1
SCHEMBL17817497 0.80 LMNA (0.59) FABP3LMNAAKT1ADRA1AESR1
SCHEMBL192297 0.80 FABP3 (0.45) FABP3LMNAAKT1ADRA1AESR1
SCHEMBL26556580 0.79 BBOX1 (0.52) FABP3LMNAAKT1ADRA1AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8063238-B2 Diamine compound having phosphorylcholine group, polymer thereof, and process for producing the polymer TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) 2011-11-22 US disclosed