Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 12/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 8/20 | 0.45 |
| ▸ | PARP1 | P09874 | 10/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15690360 | 0.78 | CDC7 (0.53) | MAPK1 | |
| SCHEMBL22990298 | 0.74 | PARP10 (0.56) | PARP10PARP11PARP1ACHEPDPK1 | |
| SCHEMBL29698302 | 0.74 | PARP10 (0.56) | PARP10PARP11PARP1ACHEPDPK1 | |
| SCHEMBL26018019 | 0.68 | GRIA1 (0.45) | PARP1 | |
| SCHEMBL24886285 | 0.67 | PARP10 (0.56) | PARP10PARP11PARP1ACHEPDPK1 | |
| SCHEMBL30197872 | 0.67 | PARP10 (0.56) | PARP10PARP11PARP1ACHERAF1 | |
| SCHEMBL29698189 | 0.67 | PARP10 (0.56) | PARP10PARP11PARP1ACHEPDPK1 | |
| SCHEMBL22982047 | 0.67 | PARP10 (0.56) | PARP10PARP11PARP1ACHEPDPK1 | |
| SCHEMBL23952300 | 0.67 | PARP10 (0.56) | PARP10PARP11PARP1ACHEKDM4E | |
| SCHEMBL23951998 | 0.67 | PARP10 (0.56) | PARP10PARP11PARP1ACHERAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |