Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 14/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20977682 | 0.79 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL26017823 | 0.72 | GRIN2D (0.41) | PARP1 | |
| SCHEMBL26018345 | 0.68 | PARP10 (0.45) | PARP1 | |
| SCHEMBL7103933 | 0.67 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL5993417 | 0.66 | UHRF1 (0.47) | GRIA1GRIA2GRIA3GRIA4ATM | |
| SCHEMBL29987830 | 0.66 | GRIA1 (0.46) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL26018020 | 0.64 | UHRF1 (0.42) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL4929162 | 0.62 | GRIA1 (0.55) | GRIA1GRIA2GRIA3GRIA4CA12 | |
| SCHEMBL6781370 | 0.62 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL1686017 | 0.62 | UHRF1 (0.40) | GRIA1GRIA2GRIA3GRIA4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |