Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 16/20 | 0.36 |
| ▸ | PARP1 | P09874 | 16/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 16/20 | 0.36 |
| ▸ | INMT | O95050 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20954967 | 0.82 | POLB (0.40) | POLBTNKSPARP1TNKS2INMT | |
| SCHEMBL26018017 | 0.80 | TNKS (0.48) | TNKSPARP1TNKS2 | |
| SCHEMBL26018420 | 0.72 | HPRT1 (0.36) | POLBTNKSPARP1TNKS2INMT | |
| SCHEMBL17086636 | 0.65 | HPGD (0.49) | POLBTNKSPARP1TNKS2HPGD | |
| SCHEMBL26017824 | 0.65 | HPGD (0.53) | POLBTNKSPARP1TNKS2HPGD | |
| SCHEMBL20955537 | 0.64 | TNKS (0.34) | TNKSPARP1TNKS2HPGD | |
| SCHEMBL20954788 | 0.62 | TNKS (0.51) | TNKSPARP1TNKS2 | |
| SCHEMBL26018020 | 0.62 | UHRF1 (0.42) | TNKSPARP1HPGD | |
| SCHEMBL18635 | 0.61 | — | — | |
| SCHEMBL27958225 | 0.61 | PIK3CD (0.59) | INMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |