Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 8/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20954817 | 0.79 | UHRF1 (0.42) | UHRF1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL15757443 | 0.79 | UHRF1 (0.42) | UHRF1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL26017824 | 0.72 | HPGD (0.53) | SMN1; SMN2ALDH1A1MAPTPARP1HPGD | |
| SCHEMBL17086636 | 0.72 | HPGD (0.49) | SMN1; SMN2ALDH1A1MAPTPARP1HPGD | |
| SCHEMBL26018101 | 0.72 | NOS1 (0.32) | ALDH1A1MAPTHPGD | |
| SCHEMBL15573568 | 0.69 | PARP1 (0.49) | UHRF1ALDH1A1PARP1TNKSPARP2 | |
| SCHEMBL18998116 | 0.68 | HTT (0.51) | SMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL9211592 | 0.66 | NPSR1 (0.41) | UHRF1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL26018017 | 0.65 | TNKS (0.48) | PARP1TNKS | |
| SCHEMBL26018019 | 0.64 | GRIA1 (0.45) | GRIA1GRIA2GRIA3GRIA4OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |