Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 8/20 | 0.58 |
| ▸ | CTSB | P07858 | 6/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272059 | 1.00 | TACR1 (0.59) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL30515231 | 0.95 | TACR1 (0.57) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL10944965 | 0.95 | TACR1 (0.57) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL10944953 | 0.95 | TACR1 (0.57) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL9364460 | 0.90 | CTSL (0.59) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL2601905 | 0.90 | CTSL (0.59) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL31397610 | 0.90 | CTSL (0.59) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL29430953 | 0.89 | CTSL (0.58) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL28332169 | 0.89 | KDM1A (0.52) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL9556498 | 0.89 | CAPN1 (0.58) | TACR1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163953-B2 | Compounds for lysosomal modulation and methods of use | UNIVERSITY OF CONNECTICUT (US) | 2012-04-24 | — | — | US | disclosed |
| US-20090281178-A1 | Compounds for Lysosomal Modulation and Methods of Use | UNIVERSITY OF CONNECTICUT | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281178-A1 | Compounds for Lysosomal Modulation and Methods of Use | GAA, GBA1, CTSA | TACR1 2078/4885CTSL 215/4885CTSB 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.