Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 8/20 | 0.58 |
| ▸ | CTSB | P07858 | 6/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2601895 | 1.00 | TACR1 (0.59) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL30515231 | 0.95 | TACR1 (0.57) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL10944965 | 0.95 | TACR1 (0.57) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL10944953 | 0.95 | TACR1 (0.57) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL9364460 | 0.90 | CTSL (0.59) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL2601905 | 0.90 | CTSL (0.59) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL31397610 | 0.90 | CTSL (0.59) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL29430953 | 0.89 | CTSL (0.58) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL28332169 | 0.89 | KDM1A (0.52) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL9556498 | 0.89 | CAPN1 (0.58) | TACR1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240392352-A1 | METHOD FOR TRANSPOSASE MEDIATED SPATIAL TAGGING AND ANALYZING GENOMIC DNA IN A BIOLOGICAL SAMPLE | 10X GENOMICS, INC. (US) | 2024-11-28 | — | — | US | claimed |
| EP-4450641-A2 | METHOD FOR TRANSPOSASE MEDIATED SPATIAL TAGGING AND ANALYZING GENOMIC DNA IN A BIOLOGICAL SAMPLE | 10x Genomics, Inc. (US) | 2024-10-23 | — | — | EP | claimed |
| US-20240093290-A1 | METHOD FOR TRANSPOSASE MEDIATED SPATIAL TAGGING AND ANALYZING GENOMIC DNA IN A BIOLOGICAL SAMPLE | 10X GENOMICS, INC. (US) | 2024-03-21 | — | — | US | claimed |
| EP-4284942-A1 | METHOD FOR TRANSPOSASE MEDIATED SPATIAL TAGGING AND ANALYZING GENOMIC DNA IN A BIOLOGICAL SAMPLE | 10X Genomics, Inc. (US) | 2023-12-06 | — | — | EP | claimed |
| US-20230201298-A1 | LIPOPROTEIN TARGETING PROTEASE INHIBITORS AND USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-06-29 | — | — | US | claimed |
| WO-2022164615-A1 | METHOD FOR TRANSPOSASE MEDIATED SPATIAL TAGGING AND ANALYZING GENOMIC DNA IN A BIOLOGICAL SAMPLE | 10X GENOMICS, INC. (US) | 2022-08-04 | — | — | WO | claimed |
| CN-117078725-B | Spatial analysis of analytes | 10X GENOMICS, INC. (US) | 2026-05-26 | — | — | CN | disclosed |
| US-20260132451-A1 | RESOLVING SPATIAL ARRAYS BY PROXIMITY-BASED DECONVOLUTION | 10X GENOMICS, INC. (US) | 2026-05-14 | — | — | US | disclosed |
| EP-4730276-A1 | SYSTEMS AND METHODS FOR TISSUE CLASSIFICATION | 10X Genomics, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260098271-A1 | METHOD FOR INCREASING RECOMBINANT PROTEIN EXPRESSION | HOFFMANN-LA ROCHE INC. (US) | 2026-04-09 | — | — | US | disclosed |
| US-20260071262-A1 | GENERATING CAPTURE PROBES FOR SPATIAL ANALYSIS | 10X GENOMICS INC (US) | 2026-03-12 | — | — | US | disclosed |
| US-12545949-B2 | Resolving spatial arrays using deconvolution | 10X GENOMICS, INC. (US) | 2026-02-10 | — | — | US | disclosed |
| US-12529094-B2 | Imaging system hardware | 10X GENOMICS, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| US-10702571-B2 | Materials for cathepsin B enhancement and methods of use | THE UNIVERSITY OF NORTH CAROLINA AT PEMBROKE (US) | 2020-07-07 | — | — | US | disclosed |
| US-20180264071-A1 | MATERIALS FOR CATHEPSIN B ENHANCEMENT AND METHODS OF USE | THE UNIVERSITY OF NORTH CAROLINA AT PEMBROKE | 2018-09-20 | — | — | US | disclosed |
| WO-2017096049-A1 | MATERIALS FOR CATHEPSIN B ENHANCEMENT AND METHODS OF USE | THE UNIVERSITY OF NORTH CAROLINA AT PEMBROKE (US) | 2017-06-08 | — | — | WO | disclosed |
| US-20160136229-A1 | MATERIALS FOR POSITIVE CATHEPSIN B MODULATION AND METHODS OF USE FOR TREATING MILD COGNITIVE IMPAIRMENT (MCI), EARLY DEMENTIA, A-SYNUCLEINOPATHY, TRAUMATIC BRAIN INJURY, CARDIOMYOPATHY, EYE DISEASE AND SKIN DAMAGE | UNIVERSITY OF NORTH CAROLINA AT PEMBROKE (US) | 2016-05-19 | — | — | US | disclosed |
| EP-3010532-A1 | MATERIALS FOR POSITIVE CATHEPSIN B MODULATION AND METHODS OF USE FOR TREATING MILD COGNITIVE IMPAIRMENT (MCI), EARLY DEMENTIA, A-SYNUCLEINOPATHY, TRAUMATIC BRAIN INJURY, CARDIOMYOPATHY, EYE DISEASE AND SKIN DAMAGE | University of North Carolina at Pembroke (US) | 2016-04-27 | — | — | EP | disclosed |
| WO-2014204956-A1 | MATERIALS FOR POSITIVE CATHEPSIN B MODULATION AND METHODS OF USE FOR TREATING MILD COGNITIVE IMPAIRMENT (MCI), EARLY DEMENTIA, A-SYNUCLEINOPATHY, TRAUMATIC BRAIN INJURY, CARDIOMYOPATHY, EYE DISEASE AND SKIN DAMAGE | UNIVERSITY OF NORTH CAROLINA AT PEMBROKE (US) | 2014-12-24 | — | — | WO | disclosed |
| WO-2005106025-A1 | METABOLIC TEST | PML APPLICATIONS LTD. (GB) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12545949-B2 | Resolving spatial arrays using deconvolution | CPSF1, BACE1, UNG | TACR1 3324/4885CTSL 12/4885CTSB 21/4885 |
| US-10702571-B2 | Materials for cathepsin B enhancement and methods of use | CTSB, CTSA, CTSE | TACR1 726/4885CTSL 16/4885CTSB 1/4885 |
| US-20260132451-A1 | RESOLVING SPATIAL ARRAYS BY PROXIMITY-BASED DECONVOLUTION | RNGTT, ADAR, CPSF1 | TACR1 2274/4885CTSL 778/4885CTSB 432/4885 |
| US-20160136229-A1 | MATERIALS FOR POSITIVE CATHEPSIN B MODULATION AND METHODS OF USE FOR TREATING MILD COGNITIVE IMPAIRMENT (MCI), EARLY DEMENTIA, A-SYNUCLEINOPATHY, TRAUMATIC BRAIN INJURY, CARDIOMYOPATHY, EYE DISEASE AND SKIN DAMAGE | CTSB, CTSA, CTSG | TACR1 963/4885CTSL 15/4885CTSB 1/4885 |
| US-20260098271-A1 | METHOD FOR INCREASING RECOMBINANT PROTEIN EXPRESSION | SPPL2A, SPPL2B, RNPEP | TACR1 3340/4885CTSL 50/4885CTSB 554/4885 |
| US-12529094-B2 | Imaging system hardware | NOTCH2, NOTCH4, NOTCH1 | TACR1 2227/4885CTSL 113/4885CTSB 374/4885 |
| US-20230201298-A1 | LIPOPROTEIN TARGETING PROTEASE INHIBITORS AND USES | HPN, SERPINB1, PEPD | TACR1 1813/4885CTSL 106/4885CTSB 77/4885 |
| US-20260071262-A1 | GENERATING CAPTURE PROBES FOR SPATIAL ANALYSIS | RNGTT, PARG, CPSF1 | TACR1 440/4885CTSL 144/4885CTSB 195/4885 |
| US-20180264071-A1 | MATERIALS FOR CATHEPSIN B ENHANCEMENT AND METHODS OF USE | CTSB, CTSA, CTSE | TACR1 726/4885CTSL 16/4885CTSB 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.