Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 4/20 | 0.40 |
| ▸ | BMP1 | P13497 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13451427 | 1.00 | GNPAT (0.41) | GNPATECE1BMP1KDM4EMAPT | |
| SCHEMBL16152186 | 0.87 | BMP1 (0.54) | GNPATECE1BMP1MMP8CHRM2 | |
| SCHEMBL13474992 | 0.83 | KDM4E (0.42) | GNPATBMP1KDM4EMAPTTHRB | |
| SCHEMBL13645142 | 0.83 | BMP1 (0.61) | GNPATECE1BMP1MMP8MMP1 | |
| SCHEMBL26019623 | 0.82 | BMP1 (0.41) | ECE1BMP1MMP2MMP9MMP8 | |
| SCHEMBL21422285 | 0.82 | ECE1 (0.53) | GNPATECE1KDM4EMAPTTHRB | |
| SCHEMBL19277912 | 0.82 | MAPT (0.38) | GNPATBMP1KDM4EMAPTTHRB | |
| SCHEMBL21398592 | 0.82 | BMP1 (0.41) | GNPATBMP1KDM4EMAPTTHRB | |
| SCHEMBL26444807 | 0.82 | GNPAT (0.53) | GNPATBMP1KDM4EMAPTTHRB | |
| SCHEMBL13637922 | 0.81 | KDM4E (0.43) | GNPATECE1KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023118359-A1 | RHABDOBRANINS AND THEIR MEDICAL USE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-06-29 | — | — | WO | disclosed |