Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 8/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 8/20 | 0.33 |
| ▸ | WNT1 | P04628 | 6/20 | 0.33 |
| ▸ | MELK | Q14680 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | YES1 | P07947 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26019795 | 0.88 | SLC6A2 (0.38) | EPHX2GSK3BDYRK1AWNT1SLC6A2 | |
| SCHEMBL24176683 | 0.88 | TACR1 (0.40) | HTR2CEPHX2ADRB2GSK3BDYRK1A | |
| SCHEMBL30603338 | 0.88 | SLC6A2 (0.38) | EPHX2GSK3BDYRK1AWNT1SLC6A2 | |
| Hydrochloric Acid SCHEMBL28682527 | 0.87 | IDO1 (0.38) | EPHX2GSK3BDYRK1AWNT1SLC6A2 | |
| SCHEMBL30866292 | 0.85 | SLC6A2 (0.43) | EPHX2NCF1CYP1A2CYP2C19SLC6A2 | |
| SCHEMBL24176694 | 0.85 | SLC6A2 (0.43) | EPHX2NCF1CYP1A2CYP2C19SLC6A2 | |
| SCHEMBL24176792 | 0.85 | DDR1 (0.37) | EPHX2GSK3BDYRK1AWNT1MELK | |
| SCHEMBL24176754 | 0.82 | SLC6A2 (0.38) | HTR2CHTR2BEPHX2GSK3BDYRK1A | |
| SCHEMBL29833333 | 0.78 | SLC6A2 (0.40) | EPHX2SLC6A2SLC6A4 | |
| SCHEMBL24177156 | 0.78 | SLC6A2 (0.40) | EPHX2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257382-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257382-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TRPC5, TRPC1, GOT1 | HTR2C 285/4885HTR2B 176/4885MKNK1 2359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.