Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | MGMT | P16455 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31190976 | 1.00 | MAOB (0.47) | MAOBMGMTMAPTSMN1; SMN2CYP2C9 | |
| SCHEMBL31190951 | 0.85 | MAOB (0.47) | MAOBMGMTMAPTSMN1; SMN2CYP2C9 | |
| SCHEMBL26022674 | 0.85 | MAOB (0.47) | MAOBMGMTMAPTSMN1; SMN2CYP2C9 | |
| SCHEMBL25359757 | 0.82 | CYP19A1 (0.58) | MAOBMAPTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL16738992 | 0.79 | MGMT (0.50) | MGMTMAPTCYP19A1RAB9ALMNA | |
| SCHEMBL6449950 | 0.77 | SMN1; SMN2 (0.45) | MAOBMAPTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL1559731 | 0.76 | MAPT (0.66) | MAOBMAPTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL12253970 | 0.75 | PTPN1 (0.47) | MGMTMAPTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL6552022 | 0.75 | MAPT (0.54) | MAOBMAPTSMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL25355454 | 0.75 | MGMT (0.46) | MAOBMGMTMAPTSMN1; SMN2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154896-A2 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |