Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPD | P32754 | 2/20 | 0.45 |
| ▸ | CTSV | O60911 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27373647 | 0.88 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2CYP2C9CYP2C19TDP1 | |
| SCHEMBL1559731 | 0.86 | MAPT (0.66) | MAPTSMN1; SMN2CYP2C9CYP2C19TDP1 | |
| SCHEMBL7289598 | 0.80 | MAPT (0.60) | MAPTSMN1; SMN2CYP2C9CYP2C19TDP1 | |
| SCHEMBL9364728 | 0.80 | TDP1 (0.51) | MAPTSMN1; SMN2TDP1L3MBTL1MEN1 | |
| SCHEMBL1162221 | 0.80 | PTGER1 (0.54) | MAPTSMN1; SMN2CYP2C9CYP2C19TDP1 | |
| SCHEMBL21402679 | 0.78 | CTSV (0.53) | MAPTSMN1; SMN2CYP2C9CYP2C19TDP1 | |
| SCHEMBL590545 | 0.78 | MAPT (0.68) | MAPTSMN1; SMN2CYP2C9CYP2C19TDP1 | |
| SCHEMBL4870470 | 0.78 | HPD (0.64) | MAPTSMN1; SMN2CYP19A1MAOBHPD | |
| SCHEMBL12921043 | 0.77 | TDP1 (0.56) | MAPTSMN1; SMN2CYP2C9CYP2C19TDP1 | |
| SCHEMBL34466860 | 0.77 | TDP1 (0.56) | MAPTSMN1; SMN2CYP2C9CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110087729-B | Bifunctional compound with quaternary ammonium salt structure | 北京硕佰医药科技有限责任公司 | 2022-04-05 | — | — | CN | disclosed |
| EP-3556435-B1 | CLASS OF BIFUNCTIONAL COMPOUNDS WITH QUATERNARY AMMONIUM SALT STRUCTURE | BEIJING SHOWBY PHARMACEUTICAL CO LTD (CN) | 2020-10-28 | — | — | EP | disclosed |
| EP-3556435-A1 | CLASS OF BIFUNCTIONAL COMPOUNDS WITH QUATERNARY AMMONIUM SALT STRUCTURE | Beijing Showby Pharmaceutical Co., Ltd. (CN) | 2019-10-23 | — | — | EP | disclosed |
| CN-110087729-A | One kind has the dual-function compound of quaternary ammonium salt structure | 北京硕佰医药科技有限责任公司 | 2019-08-02 | — | — | CN | disclosed |
| EP-1082293-B1 | FORMOTEROL POLYMORPHS | SEPRACOR INC (US) | 2004-02-18 | — | — | EP | disclosed |
| EP-1093450-B1 | DESFORMOTEROL AND PROCESS FOR ITS PREPARATION | SEPRACOR INC (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002083079-A9 | AEROSOL COMPOSITIONS CONTAINING FORMOTEROL FOR DELIVERY TO THE LUNGS VIA NEBULIZATION | DEY L P (US) | 2003-04-10 | — | — | WO | disclosed |
| EP-0938467-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE ISOMERS OF FORMOTEROL | SEPRACOR INC (US) | 2002-06-12 | — | — | EP | disclosed |
| US-6268533-B1 | REACTING 4-BENZYLOXY-3-FORMAMIDOSTYRENE OXIDE WITH AN OPTICALLY PURE 4-METHOXY-.ALPHA.-METHYL-N-(PHENYLMETHYL)BENZENEETHANAMINE FOLLOWED BY REDUCTION TO PRODUCE FORMOTEROL | SEPRACOR INC. | 2001-07-31 | — | — | US | disclosed |
| EP-1093450-A1 | DESFORMOTEROL AND PROCESS FOR ITS PREPARATION | Sepracor Inc. (US) | 2001-04-25 | — | — | EP | disclosed |
| EP-1082293-A2 | FORMOTEROL POLYMORPHS | Sepracor Inc. (US) | 2001-03-14 | — | — | EP | disclosed |
| US-6071971-A | FOR TREATING PULMONARY DISORDERS | SEPRACOR INC. (US) | 2000-06-06 | — | — | US | disclosed |
| WO-2000021487-A2 | FORMOTEROL POLYMORPHS | SEPRACOR INC. (US) | 2000-04-20 | — | — | WO | disclosed |
| US-6040344-A | CRYSTALLINE R,R-FORMOTEROL L-(+)-TARTRATE. | SEPRACOR INC. (US) | 2000-03-21 | — | — | US | disclosed |
| WO-1999067198-A1 | DESFORMOTEROL AND PROCESS FOR ITS PREPARATION | SEPRACOR INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| US-5965622-A | BRONCHODILATORS; HIGHLY SELECTIVE BETA 2-ADRENERGIC RECEPTOR AGONIST; RESPIRATORY DISORDERS, E.G. ASTHMA, BRONCHITIS; REDUCTION OF A PROTECTED NITRO DERIVATIVE; STEREOSPECIFIC | SEPRACOR INC. (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0938467-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE ISOMERS OF FORMOTEROL | SEPRACOR, INC. (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998021175-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE ISOMERS OF FORMOTEROL | SEPRACOR, INC. (US) | 1998-05-22 | — | — | WO | disclosed |