Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628149 | 0.89 | SHBG (0.41) | HRH3SHBGKDM4EDPP4 | |
| SCHEMBL23467566 | 0.89 | SHBG (0.41) | HRH3SHBGKDM4EDPP4 | |
| SCHEMBL23114309 | 0.89 | SHBG (0.41) | HRH3SHBGKDM4EDPP4 | |
| SCHEMBL23784287 | 0.81 | L3MBTL3 (0.42) | HRH3OPRL1OPRM1TP53SIGMAR1 | |
| SCHEMBL12026451 | 0.81 | HRH3 (0.40) | HRH3OPRL1OPRD1OPRK1 | |
| SCHEMBL22456358 | 0.80 | TSHR (0.40) | HRH3OPRL1OPRM1TP53SIGMAR1 | |
| SCHEMBL24485993 | 0.79 | HRH3 (0.43) | HRH3OPRL1OPRM1TP53CHRM1 | |
| SCHEMBL22280407 | 0.79 | SMN1; SMN2 (0.36) | HRH3OPRL1KDM4ETP53 | |
| SCHEMBL19098326 | 0.78 | OPRL1 (0.34) | HRH3OPRL1OPRD1OPRK1OPRM1 | |
| SCHEMBL12073908 | 0.77 | DPP4 (0.44) | HRH3SHBGKDM4EDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640248-B1 | AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) | 2023-08-23 | — | — | EP | disclosed |