Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455250 | 0.79 | MAOA (0.46) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL22374283 | 0.79 | TDP1 (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL21455400 | 0.77 | TDP1 (0.39) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL24311398 | 0.77 | KMT2A (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL13223925 | 0.74 | TDP1 (0.48) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL19575618 | 0.73 | KMT2A (0.38) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL4714065 | 0.73 | TDP1 (0.52) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL125503 | 0.73 | TDP1 (0.52) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL20909964 | 0.72 | CA1 (0.35) | TDP1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL16594495 | 0.72 | TDP1 (0.47) | TDP1MAOAMAOBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |