Bromobenzene

Bromobenzene

SCHEMBL260235

Brc1ccccc1.F[B-](F)(F)F

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.73
TDP1 Q9NUW8 1/20 0.73
MAPK1 P28482 3/20 0.58
CYP2A6 P11509 1/20 0.44
NPC1 O15118 3/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
AKR1C3 P42330 2/20 0.38
HTR2A P28223 1/20 0.37
NR1H4 Q96RI1 1/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromobenzene SCHEMBL28830047 1.00 ALDH1A1 (0.73) ALDH1A1TDP1MAPK1CYP2A6NPC1
Bromobenzene SCHEMBL27592660 0.97 ALDH1A1 (0.69) ALDH1A1TDP1MAPK1CYP2A6NPC1
Bromobenzene SCHEMBL9893634 0.97 ALDH1A1 (0.69) ALDH1A1TDP1MAPK1CYP2A6NPC1
Bromobenzene SCHEMBL260618 0.91 ALDH1A1 (0.61) ALDH1A1TDP1MAPK1CYP2A6NPC1
Bromobenzene SCHEMBL28540774 0.91 ALDH1A1 (0.61) ALDH1A1TDP1MAPK1CYP2A6NPC1
Bromobenzene SCHEMBL537562 0.86 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1CYP2A6NPC1
Bromobenzene SCHEMBL1331176 0.86
Bromobenzene SCHEMBL20537325 0.86 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1CYP2A6NPC1
Bromobenzene SCHEMBL2158200 0.86
Bromobenzene SCHEMBL1542 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121318-B Biheteroaromatic hydrocarbon compound and preparation method thereof 浙江工业大学 2022-04-26 CN claimed
CN-118724934-A Mechanochemical synthesis of alpha-haloalkylboron esters 西安交通大学 2024-10-01 CN disclosed
CN-114981655-A Detection of nicotine, cannabinoids and drugs of abuse on the surface of a vaping device and in a vaping liquid formulation 韦里特克美国有限公司 2022-08-30 CN disclosed
CN-113121318-B Biheteroaromatic hydrocarbon compound and preparation method thereof 浙江工业大学 2022-04-26 CN disclosed
CN-113121318-A Biheteroaromatic hydrocarbon compound and preparation method thereof 浙江工业大学 2021-07-16 CN disclosed
US-8133549-B2 Method for modifying insulating or semi-conductive surfaces, and resulting products ALCHIMER (FR) 2012-03-13 US disclosed
US-20090301862-A1 METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS ALCHIMEDICS (FR) 2009-12-10 US disclosed