Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromobenzene SCHEMBL28830047 | 0.97 | ALDH1A1 (0.73) | ALDH1A1TDP1MAPK1CYP2A6NPC1 | |
| Bromobenzene SCHEMBL260235 | 0.97 | ALDH1A1 (0.73) | ALDH1A1TDP1MAPK1CYP2A6NPC1 | |
| Bromobenzene SCHEMBL27592660 | 0.94 | ALDH1A1 (0.69) | ALDH1A1TDP1MAPK1CYP2A6NPC1 | |
| Bromobenzene SCHEMBL260618 | 0.88 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1CYP2A6NPC1 | |
| Bromobenzene SCHEMBL28540774 | 0.88 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPK1CYP2A6NPC1 | |
| Bromobenzene SCHEMBL27541615 | 0.87 | — | — | |
| Bromobenzene SCHEMBL537562 | 0.83 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1CYP2A6NPC1 | |
| Bromobenzene SCHEMBL1331176 | 0.83 | — | — | |
| Bromobenzene SCHEMBL20537325 | 0.83 | ALDH1A1 (1.00) | ALDH1A1TDP1MAPK1CYP2A6NPC1 | |
| Bromobenzene SCHEMBL2158200 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845538-A | Furan-fused boron-nitrogen heterodihydropyrene and synthetic method thereof | 天津理工大学 | 2021-12-28 | — | — | CN | claimed |
| CN-118930565-A | Synthesis method of B (4) -aryl-B (9) -amide-o-carborane derivative | 兰州大学 | 2024-11-12 | — | — | CN | disclosed |
| CN-111620896-B | Preparation method of tetra-coordinated N, N-chelated diaryl borate compound with 8-aminoquinoline derivative as bidentate ligand | 石河子大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-110256306-B | Ortho-sulfonamide substituted diaryl iodine compound and preparation method and application thereof | 华东理工大学 | 2021-11-12 | — | — | CN | disclosed |
| CN-113150018-A | Four-coordination N, N-chelating monoaryl monofluoroborate compound and preparation method thereof | 石河子大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-111620896-A | Preparation method of tetra-coordinated N, N-chelated diaryl borate compound with 8-aminoquinoline derivative as bidentate ligand | 石河子大学 | 2020-09-04 | — | — | CN | disclosed |
| US-9908819-B1 | Printing method for production a ceramic green body | WZR ceramic solutions GmbH (DE) | 2018-03-06 | — | — | US | disclosed |
| US-20150315127-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2015-11-05 | — | — | US | disclosed |
| US-9024071-B2 | Therapeutic compounds | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-05-05 | — | — | US | disclosed |
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ALDH1A1 4010/4885TDP1 3577/4885MAPK1 2307/4885 |
| US-20150315127-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ALDH1A1 4010/4885TDP1 3577/4885MAPK1 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.