Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 8/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26008657 | 0.84 | ALDH1A1 (1.00) | ALDH1A1KDM4ERAB9ANPC1CHEK1 | |
| SCHEMBL29227467 | 0.79 | CRBN (0.71) | CRBN | |
| SCHEMBL26023748 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4ERAB9ANPC1CHEK1 | |
| SCHEMBL26023753 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4ERAB9ANPC1CHEK1 | |
| SCHEMBL12156605 | 0.76 | RAB9A (0.76) | ALDH1A1KDM4ERAB9ANPC1CHEK1 | |
| SCHEMBL14748349 | 0.75 | RAB9A (0.66) | ALDH1A1KDM4ERAB9ANPC1CCR2 | |
| SCHEMBL13162947 | 0.73 | ALDH1A1 (0.74) | ALDH1A1KDM4ERAB9ANPC1CHEK1 | |
| SCHEMBL8381645 | 0.72 | RAB9A (0.75) | ALDH1A1KDM4ERAB9ANPC1CHEK1 | |
| SCHEMBL15087624 | 0.72 | RAB9A (0.75) | ALDH1A1KDM4ERAB9ANPC1CHEK1 | |
| SCHEMBL20496795 | 0.72 | ALDH1A1 (0.72) | ALDH1A1KDM4ERAB9ANPC1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154896-A2 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |