SCHEMBL26024367

SCHEMBL26024367

c1ccc(-c2nc(-c3ccc4c(c3)oc3ccc(-n5c6ccccc6c6ccccc65)cc34)nc(-c3cccc4c3oc3cc(-c5ccc(-c6nc(-c7ccc8c(c7)oc7ccccc78)nc(-c7ccc8c(c7)oc7ccc(-n9c%10ccccc%10c%10ccccc%109)cc78)n6)cc5)ccc34)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.38
PRKDC P78527 3/20 0.38
MAPT P10636 4/20 0.33
KDM4E B2RXH2 2/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
PIM1 P11309 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HPGD P15428 1/20 0.33
PTGER4 P35408 1/20 0.33
POLB P06746 1/20 0.33
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21883211 0.98 PRKDC (0.36) ALOX5PRKDCMAPTKDM4ETSHR
SCHEMBL25926331 0.98 ALOX5 (0.37) ALOX5PRKDCMAPTKDM4ETSHR
SCHEMBL21668798 0.98 ALOX5 (0.39) ALOX5PRKDCMAPTKDM4ETSHR
SCHEMBL24215953 0.98 ALOX5 (0.39) ALOX5PRKDCMAPTKDM4ETSHR
SCHEMBL21883213 0.97 PRKDC (0.36) ALOX5PRKDCMAPTKDM4ETSHR
SCHEMBL25954293 0.97 PRKDC (0.36) ALOX5PRKDCMAPTKDM4ETSHR
SCHEMBL25926342 0.97 ALOX5 (0.36) ALOX5PRKDCMAPTKDM4ETSHR
SCHEMBL25926366 0.97 ALOX5 (0.36) ALOX5PRKDCMAPTKDM4ETSHR
SCHEMBL25458461 0.96 PRKDC (0.35) ALOX5PRKDCMAPTKDM4ETSHR
SCHEMBL25458396 0.95 PRKDC (0.34) ALOX5PRKDCMAPTPIM1CSNK2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed