SCHEMBL21883213

SCHEMBL21883213

c1ccc(-c2ccc3c(c2)c2ccccc2n3-c2ccc3oc4cc(-c5nc(-c6ccccc6)nc(-c6cccc7c6oc6ccccc67)n5)ccc4c3c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.36
ALOX5 P09917 2/20 0.36
PIM1 P11309 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
MAPT P10636 3/20 0.32
PLA2G2A P14555 2/20 0.32
PLA2G4A P47712 2/20 0.32
KDM4E B2RXH2 2/20 0.32
TSHR P16473 2/20 0.32
CHEK2 O96017 1/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 1/20 0.32
PTGER4 P35408 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25954293 1.00 PRKDC (0.36) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL25458461 0.99 PRKDC (0.35) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL25458396 0.98 PRKDC (0.34) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL24217179 0.97 ALOX5 (0.36) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL25458460 0.97 PRKDC (0.35) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL25954247 0.97 ALOX5 (0.38) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL26024367 0.97 ALOX5 (0.38) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL25637966 0.96 PRKDC (0.36) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL25458483 0.96 ALOX5 (0.35) PRKDCALOX5PIM1CSNK2A2CSNK2B
SCHEMBL25954304 0.96 ALOX5 (0.39) PRKDCALOX5MAPTKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11785844-B2 Organic light emitting device, method for manufacturing same and composition for organic material layer LT MATERIALS CO., LTD. (KR) 2023-10-10 US disclosed
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element LT MATERIALS CO., LTD. (KR) 2022-07-12 US disclosed
US-20210057651-A1 ORGANIC LIGHT EMITTING DEVICE, METHOD FOR MANUFACTURING SAME AND COMPOSITION FOR ORGANIC MATERIAL LAYER LT MATERIALS CO., LTD. (KR) 2021-02-25 US disclosed
US-20200381629-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2020-12-03 US disclosed
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT HEESUNG MATERIAL LTD. (KR) 2020-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11387418-B2 Organic light emitting element and composition for organic material layer in organic light emitting element CRY1, CYBA, L1CAM PRKDC 4167/4885ALOX5 721/4885PIM1 1553/4885
US-20200119285-A1 ORGANIC LIGHT EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER IN ORGANIC LIGHT EMITTING ELEMENT CRY1, CYBA, L1CAM PRKDC 4167/4885ALOX5 721/4885PIM1 1553/4885
US-20200381629-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 PRKDC 4595/4885ALOX5 751/4885PIM1 1259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.