SCHEMBL26025

SCHEMBL26025

CN(CCOC(=O)CI)c1ccc([N+](=O)[O-])c2nonc12

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
GSTP1 P09211 15/20 0.47
GSTM2 P28161 15/20 0.47
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
KCNH2 Q12809 1/20 0.44
IDO1 P14902 1/20 0.39
CNR2 P34972 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6123423 0.89 MEN1 (0.51) MEN1KMT2AGSTP1GSTM2ALDH1A1
SCHEMBL6510158 0.84 MEN1 (0.49) MEN1KMT2AGSTP1GSTM2ALDH1A1
SCHEMBL131795 0.83 MEN1 (0.52) MEN1KMT2AGSTP1GSTM2KCNH2
SCHEMBL6951880 0.83 MEN1 (0.52) MEN1KMT2AGSTP1GSTM2KCNH2
SCHEMBL14140891 0.78 MEN1 (0.54) MEN1KMT2AGSTP1GSTM2MAPT
SCHEMBL26054240 0.77 MEN1 (0.56) MEN1KMT2AGSTP1GSTM2
SCHEMBL18007677 0.77 KMT2A (0.61) MEN1KMT2AGSTP1GSTM2HTT
SCHEMBL23612900 0.76 MEN1 (0.52) MEN1KMT2AGSTP1GSTM2KCNH2
SCHEMBL3063567 0.76 MEN1 (0.52) MEN1KMT2AGSTP1GSTM2KCNH2
SCHEMBL4557847 0.76 GSTP1 (0.44) MEN1KMT2AGSTP1GSTM2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346641-A1 COMPOSITIONS AND METHODS FOR THIN FILAMENT MODULATION UNIV ARIZONA (US) 2025-11-13 US claimed
US-20250341524-A1 FLUORESCENTLY-LABELED F-ACTIN PROTEIN BIOSENSORS AND METHODS OF HIGH-THROUGHPUT DRUG DISCOVERY UNIV ARIZONA (US) 2025-11-06 US claimed
US-20240168032-A1 GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-23 US claimed
EP-3377898-B1 THERMOSTABLE GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-3377904-B1 UREA BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
EP-3377897-B1 LACTATE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
US-20240019442-A1 BIOSENSOR FOR DETECTING STRUCTURAL CHANGES IN HUMAN CARDIAC MUSCLE PROTEIN NATIONAL INSTITUTES OF HEALTH 2024-01-18 US claimed
US-11852637-B2 Bicarbonate biosensors, calcium biosensors, and uses thereof DUKE UNIVERSITY (US) 2023-12-26 US claimed
US-20230349911-A1 COMPOSITIONS AND METHODS TO QUANTIFY THE BINDING INTERACTIONS OF MYOSIN BINDING-PROTEIN C (MYBP-C) NATIONAL INSTITUTES OF HEALTH 2023-11-02 US claimed
US-20220244266-A1 GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2022-08-04 US claimed
US-7202089-B2 Detection of stroke in mammals; provide body fluid sample, incubate with fatty acid binding protein and fluorescent agent, measure fluorescence, evaluate for stroke KLEINFELD ALAN 2007-04-10 US claimed
WO-2006052860-A2 MODULATORS OF RETINOL-RETINOL BINDING PROTEIN (RBP)-TRANSTHYRETIN (TTR) COMPLEX FORMATION SIRION THERAPEUTICS, INC. (US) 2006-05-18 WO claimed
US-20060094063-A1 Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation SYTERA, INC. (US) 2006-05-04 US claimed
EP-1424931-A4 EARLY DIAGNOSIS OF STROKE KLEINFELD ALAN M (US) 2004-10-06 EP claimed
US-6750030-B2 MIXING SERUM SAMPLE WITH AQUEOUS SOLUTION AND WITH A REAGENT COMPRISING A FATTY ACID BINDING PROTEIN LABELED WITH A FLUORESCENT MOIETY; MEASURING FLUORESCENCE; DETERMINING CONCENTRATION OF FREE FATTY ACID TORREY PINES INSTITUTE FOR MOLECULAR STUDIES 2004-06-15 US claimed
EP-1424931-A2 EARLY DIAGNOSIS OF STROKE KLEINFELD, Alan M. (US) 2004-06-09 EP claimed
WO-2003024306-A2 EARLY DIAGNOSIS OF STROKE KLEINFELD ALAN (US) 2003-03-27 WO claimed
US-20030054412-A1 Early diagnosis of stroke KLEINFELD ALAN (US) 2003-03-20 US claimed
US-20020160537-A1 Mixing serum sample with aqueous solution and with a reagent comprising a fatty acid binding protein labeled with a fluorescent moiety; measuring fluorescence; determining concentration of free fatty acid KLEINFELD ALAN M (US) 2002-10-31 US claimed
WO-1998057171-A1 METHOD OF DETECTION OF CARDIAC ISCHEMIA USING FATTY ACID BINDING PROTEIN MEDICAL BIOLOGY INSTITUTE (US) 1998-12-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240168032-A1 GLUCOSE BIOSENSORS AND USES THEREOF GCK, GCKR, SLC2A4 MEN1 2391/4885KMT2A 4044/4885GSTP1 688/4885
US-20220244266-A1 GLUCOSE BIOSENSORS AND USES THEREOF GCK, GCKR, SLC2A4 MEN1 2391/4885KMT2A 4044/4885GSTP1 688/4885
US-20060094063-A1 Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation RBP1, TTR, RBP4 MEN1 4500/4885KMT2A 4838/4885GSTP1 3209/4885
US-11852637-B2 Bicarbonate biosensors, calcium biosensors, and uses thereof CA2, CASR, CACYBP MEN1 1448/4885KMT2A 4560/4885GSTP1 2915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.