Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13826229 | 0.77 | ALDH1A1 (0.58) | ALDH1A1TSHRTDP1TAS1R3TAS1R1 | |
| SCHEMBL11806185 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1TAS1R3TAS1R1 | |
| SCHEMBL52040 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1TAS1R3TAS1R1 | |
| SCHEMBL12447801 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1TAS1R3TAS1R1 | |
| SCHEMBL1760727 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1TAS1R3TAS1R1 | |
| SCHEMBL12579970 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1TAS1R3TAS1R1 | |
| SCHEMBL8966417 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1TAS1R3TAS1R1 | |
| SCHEMBL28831140 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1TAS1R3TAS1R1 | |
| SCHEMBL12447800 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1TAS1R3TAS1R1 | |
| Hydrogen Peroxide SCHEMBL28624206 | 0.74 | ALDH1A1 (0.85) | ALDH1A1TSHRTDP1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3429693-B1 | NAPI2B-TARGETED ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | MERSANA THERAPEUTICS INC (US) | 2023-08-23 | — | — | EP | disclosed |