SCHEMBL1760727

SCHEMBL1760727

C=Cc1ccc(C(=C)C)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 3/20 0.41
HDAC8 Q9BY41 2/20 0.41
TAS1R3 Q7RTX0 3/20 0.41
TAS1R1 Q7RTX1 3/20 0.41
CYP3A4 P08684 3/20 0.39
CYP2C9 P11712 3/20 0.39
CYP2C19 P33261 3/20 0.39
TP53 P04637 2/20 0.38
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
TRPA1 O75762 1/20 0.36
MAPT P10636 3/20 0.34
MEN1 O00255 1/20 0.34
CYP2D6 P10635 1/20 0.34
KMT2A Q03164 1/20 0.34
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Vinylphenol SCHEMBL7196346 0.91 ESR1 (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19TP53
Styrene SCHEMBL315930 0.84 ALDH1A1 (0.61) ALDH1A1TSHRTDP1HDAC8CYP3A4
SCHEMBL472890 0.83 ALDH1A1 (0.48) ALDH1A1TSHRTDP1CYP3A4CYP2C9
SCHEMBL56361 0.81 MAPT (0.40) ALDH1A1TDP1ESR1ESR2MAPT
Styrene SCHEMBL2941460 0.81 ALDH1A1 (0.56) ALDH1A1TSHRTDP1HDAC8CYP3A4
SCHEMBL5507106 0.80 ESR1 (0.44) ALDH1A1TAS1R3TAS1R1CYP3A4CYP2C9
SCHEMBL123485 0.80 ALDH1A1 (0.55) ALDH1A1TSHRTDP1HDAC8CYP3A4
SCHEMBL9502648 0.79 ALDH1A1 (0.48) ALDH1A1TSHRTDP1TAS1R3TAS1R1
SCHEMBL8520742 0.79 ALDH1A1 (0.61) ALDH1A1TSHRTDP1HDAC8TAS1R3
Styrene SCHEMBL27519908 0.79 ALDH1A1 (0.54) ALDH1A1TSHRTDP1HDAC8CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12428550-B2 Resin composition and uses thereof TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2025-09-30 US claimed
US-20240150567-A1 RESIN COMPOSITION AND USES THEREOF TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2024-05-09 US claimed
CN-117917444-A Resin composition and use thereof 台燿科技股份有限公司 2024-04-23 CN claimed
EP-1346824-B1 Compositions and methods for selectively cross-linking films and film articles resulting therefrom CRYOVAC INC (US) 2009-05-13 EP claimed
EP-0269275-B1 Thermoplastic elastomer composition MITSUI PETROCHEMICAL IND (JP) 1994-05-11 EP claimed
EP-0266982-B1 Laminated and molded article prepared therefrom MITSUI PETROCHEMICAL IND (JP) 1994-04-27 EP claimed
EP-0155899-B1 BINDER FOR CHEMICAL AGENTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-01-03 EP claimed
US-4613633-A FOR PAPERBOAD COATING NIPPON ZEON CO., LTD. (JP) 1986-09-23 US claimed
EP-0185602-A1 Moulding composition for use in wheels THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-06-25 EP claimed
US-4569957-A CREEP RESISTANT; DICYCLOPENTADIENE POLYESTER AND PHENOLIC-NOVALAK ACRYLIC ESTER RESIN THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-02-11 US claimed
EP-0155899-A2 Binder for chemical agents THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-09-25 EP claimed
US-4539346-A Binder for chemical agents THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-09-03 US claimed
US-4489184-A Molding composition CITICORP NORTH AMERICA, INC., AS "AGENT" 1984-12-18 US claimed
US-4000958-A Method for treating leather SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-01-04 US claimed
US-3950281-A DIENE RUBBERS, CURABLE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-04-13 US claimed
US-12559581-B2 Ethylene-copolymers and catalyst mixture for making ethylene copolymers ARLANXEO NETHERLANDS B.V. (NL) 2026-02-24 US disclosed
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor BRILLIANT LIGHT POWER, INC. (US) 2026-02-03 US disclosed
US-3985540-A Metal complexes of hydroxyquinoline and polymeric porous granules GAF CORPORATION (US) 1976-10-12 US disclosed
US-3954682-A GRANULES OR BEADS GAF CORPORATION (US) 1976-05-04 US disclosed
US-3950281-A DIENE RUBBERS, CURABLE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559581-B2 Ethylene-copolymers and catalyst mixture for making ethylene copolymers EEF1D, COG7, CCND1 ALDH1A1 3591/4885TSHR 3104/4885TDP1 2608/4885
US-12540073-B2 Heterogeneous hydrogen-catalyst solid fuel reaction mixture and reactor SCO2, SOD1, HAO2 ALDH1A1 3874/4885TSHR 830/4885TDP1 4237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.