SCHEMBL26027705

SCHEMBL26027705

CNCCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])C(=O)Nc1ccc(CO)cc1OC

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 18/20 0.45
▸ ITGB1 P05556 1/20 0.37
▸ ITGA5 P08648 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26027291 0.92 FOLH1 (0.40) FOLH1
SCHEMBL25361469 0.89 FOLH1 (0.41) FOLH1
SCHEMBL25361483 0.89 FOLH1 (0.41) FOLH1
SCHEMBL26015579 0.89 ITGB1 (0.43) FOLH1ITGB1ITGA5
SCHEMBL25361531 0.85 CALCRL (0.43) FOLH1
SCHEMBL25361684 0.82 FOLH1 (0.37) FOLH1
SCHEMBL25361668 0.82 FOLH1 (0.37) FOLH1
SCHEMBL25361502 0.81 FOLH1 (0.41) FOLH1
SCHEMBL26015665 0.81 SSTR3 (0.41) FOLH1ITGB1ITGA5
SCHEMBL26015660 0.81 FOLH1 (0.41) FOLH1ITGB1ITGA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF NDC1, KIFC1, SDCBP FOLH1 433/4885ITGB1 2939/4885ITGA5 3119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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