Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14453902 | 0.87 | HRH3 (0.41) | HRH3L3MBTL3L3MBTL1MBTD1TLR9 | |
| SCHEMBL22456342 | 0.87 | HRH3 (0.41) | HRH3L3MBTL3L3MBTL1MBTD1TLR9 | |
| SCHEMBL23384368 | 0.85 | KDM4E (0.42) | HRH3L3MBTL3L3MBTL1MBTD1KDM4E | |
| SCHEMBL13744835 | 0.85 | KDM4E (0.42) | HRH3L3MBTL3L3MBTL1MBTD1KDM4E | |
| SCHEMBL23384260 | 0.85 | HRH3 (0.40) | HRH3L3MBTL3L3MBTL1MBTD1TLR9 | |
| SCHEMBL24726517 | 0.85 | HRH3 (0.40) | HRH3L3MBTL3L3MBTL1MBTD1TLR9 | |
| SCHEMBL22456382 | 0.83 | HRH3 (0.49) | HRH3L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL24828016 | 0.82 | HRH3 (0.33) | HRH3L3MBTL3L3MBTL1MBTD1KDM4E | |
| SCHEMBL22456360 | 0.81 | L3MBTL3 (0.42) | HRH3L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL22175014 | 0.81 | KDM4E (0.43) | HRH3KDM4EALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640248-B1 | AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) | 2023-08-23 | — | — | EP | disclosed |