Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | FPR3 | P25089 | 4/20 | 0.41 |
| ▸ | FPR2 | P25090 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924681 | 1.00 | KDM4E (0.49) | KDM4ELMNANPC1NFKB1RAB9A | |
| SCHEMBL26031407 | 0.94 | TDP1 (0.50) | KDM4ELMNANPC1NFKB1RAB9A | |
| SCHEMBL19186278 | 0.94 | TDP1 (0.50) | KDM4ELMNANPC1NFKB1RAB9A | |
| SCHEMBL13107792 | 0.83 | KDM4E (0.41) | KDM4ELMNANPC1NFKB1RAB9A | |
| SCHEMBL9925978 | 0.79 | KDM4E (0.42) | KDM4ELMNANPC1NFKB1RAB9A | |
| SCHEMBL10124090 | 0.78 | KDM4E (0.59) | KDM4ELMNANPC1NFKB1RAB9A | |
| SCHEMBL14392991 | 0.78 | KDM4E (0.59) | KDM4ELMNANPC1NFKB1RAB9A | |
| SCHEMBL11064769 | 0.76 | KDM4E (0.61) | KDM4ELMNANPC1NFKB1RAB9A | |
| SCHEMBL11064771 | 0.76 | KDM4E (0.61) | KDM4ELMNANPC1NFKB1RAB9A | |
| SCHEMBL19822715 | 0.76 | EPHX1 (0.37) | KDM4ELMNANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210301078-A1 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-30 | — | — | US | disclosed |
| US-20210283054-A1 | HIGH DENSITY PEPTIDE POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-09-16 | — | — | US | disclosed |
| US-11072681-B2 | Compositions and methods of making polymerizing nucleic acids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-27 | — | — | US | disclosed |
| US-10980744-B2 | High density peptide polymers | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-04-20 | — | — | US | disclosed |
| US-20180169275-A1 | POLYMERIC MICELLAR NANOPARTICLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-06-21 | — | — | US | disclosed |
| US-20180169275-A1 | POLYMERIC MICELLAR NANOPARTICLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-06-21 | — | — | US | disclosed |
| US-20180042843-A1 | HIGH DENSITY PEPTIDE POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-02-15 | — | — | US | disclosed |
| US-20180042843-A1 | HIGH DENSITY PEPTIDE POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-02-15 | — | — | US | disclosed |
| US-20170327633-A1 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-11-16 | — | — | US | disclosed |
| US-20170327633-A1 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180169275-A1 | POLYMERIC MICELLAR NANOPARTICLES | PHOSPHO1, LIPA, PITPNB | KDM4E 4470/4885LMNA 329/4885NPC1 55/4885 |
| US-11072681-B2 | Compositions and methods of making polymerizing nucleic acids | RNGTT, NSUN2, POLN | KDM4E 4223/4885LMNA 79/4885NPC1 1860/4885 |
| US-20180042843-A1 | HIGH DENSITY PEPTIDE POLYMERS | ERMP1, PARL, PRAP1 | KDM4E 4561/4885LMNA 2706/4885NPC1 1559/4885 |
| US-10980744-B2 | High density peptide polymers | IAPP, LCP1, LNPEP | KDM4E 4666/4885LMNA 2117/4885NPC1 3281/4885 |
| US-20170327633-A1 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS | RNGTT, NSUN2, POLN | KDM4E 4223/4885LMNA 79/4885NPC1 1860/4885 |
| US-20210301078-A1 | COMPOSITIONS AND METHODS OF MAKING POLYMERIZING NUCLEIC ACIDS | RNGTT, NSUN2, POLN | KDM4E 4223/4885LMNA 79/4885NPC1 1860/4885 |
| US-20210283054-A1 | HIGH DENSITY PEPTIDE POLYMERS | IAPP, LCP1, LNPEP | KDM4E 4666/4885LMNA 2117/4885NPC1 3281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.