SCHEMBL26032276

SCHEMBL26032276

CNO[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 2/20 0.44
FOLH1 Q04609 6/20 0.44
RNPEP Q9H4A4 1/20 0.41
SLC7A5 Q01650 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38
CPA1 P15085 1/20 0.38
CACNA2D1 P54289 2/20 0.36
CACNB3 P54284 1/20 0.36
CACNA1C Q13936 1/20 0.36
PGR P06401 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR2B P41595 1/20 0.36
CACNA2D2 Q9NY47 1/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26940451 0.77 LAP3 (0.47) LAP3FOLH1RNPEPSLC7A5ALDH1A1
SCHEMBL13765212 0.76 LAP3 (0.44) LAP3FOLH1RNPEPSLC7A5ALDH1A1
SCHEMBL18414062 0.76 CYP2D6 (0.42) KMT2A
SCHEMBL24307956 0.75 LAP3 (0.50) LAP3FOLH1RNPEPSLC7A5ALDH1A1
SCHEMBL8072286 0.75 LAP3 (0.48) LAP3FOLH1RNPEPSLC7A5ALDH1A1
SCHEMBL13461523 0.75 LAP3 (0.48) LAP3FOLH1RNPEPSLC7A5ALDH1A1
SCHEMBL30852968 0.74 LAP3 (0.44) LAP3FOLH1RNPEPSLC7A5ALDH1A1
SCHEMBL19301334 0.73 FOLH1 (0.50) LAP3FOLH1RNPEPSLC7A5ALDH1A1
SCHEMBL11789757 0.73 LAP3 (0.52) LAP3FOLH1RNPEPSLC7A5ALDH1A1
SCHEMBL9275334 0.73 LAP3 (0.52) LAP3FOLH1RNPEPSLC7A5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265104-A1 NOVEL HETEROCYCLIC COMPOUNDS Prism BioLab Co., Ltd. (JP) 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265104-A1 NOVEL HETEROCYCLIC COMPOUNDS MKI67, CCNI, KRAS LAP3 3198/4885FOLH1 2880/4885RNPEP 3997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.