SCHEMBL26940451

SCHEMBL26940451

CC(C)C[C@H](OC(C)C)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 2/20 0.47
RNPEP Q9H4A4 1/20 0.44
SLC7A5 Q01650 1/20 0.44
FOLH1 Q04609 6/20 0.42
CACNA2D1 P54289 2/20 0.39
ALDH1A1 P00352 2/20 0.39
CACNB3 P54284 1/20 0.39
CACNA1C Q13936 1/20 0.39
PGR P06401 1/20 0.39
ADRA1A P35348 1/20 0.39
HTR2B P41595 1/20 0.39
CACNA2D2 Q9NY47 1/20 0.39
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36
CPA1 P15085 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30852968 0.82 LAP3 (0.44) LAP3RNPEPSLC7A5FOLH1CACNA2D1
SCHEMBL13554081 0.81 LAP3 (0.35) LAP3RNPEPSLC7A5FOLH1CACNA2D1
SCHEMBL30497659 0.81 SLC1A3 (0.41) LAP3RNPEPSLC7A5FOLH1SLC1A3
SCHEMBL13554106 0.81 LAP3 (0.35) LAP3RNPEPSLC7A5FOLH1CACNA2D1
SCHEMBL12141288 0.79 TSHR (0.46) LAP3RNPEPSLC7A5FOLH1CACNA2D1
SCHEMBL13461523 0.78 LAP3 (0.48) LAP3RNPEPSLC7A5FOLH1CACNA2D1
SCHEMBL20276339 0.78 OR51E2 (0.36) LAP3RNPEPSLC7A5
SCHEMBL26940415 0.78 SMN1; SMN2 (0.40) LAP3RNPEPALDH1A1ADRA1ASLC1A3
SCHEMBL3206858 0.78 SMN1; SMN2 (0.40) LAP3RNPEPALDH1A1ADRA1ASLC1A3
SCHEMBL8072286 0.78 LAP3 (0.48) LAP3RNPEPSLC7A5FOLH1CACNA2D1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399297-A1 Novel Glutamine Analogs GLUL, GATD3, GLS LAP3 770/4885RNPEP 2535/4885SLC7A5 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.