Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.76 |
| ▸ | AXL | P30530 | 11/20 | 0.64 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.63 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.63 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.63 |
| ▸ | TYRO3 | Q06418 | 10/20 | 0.60 |
| ▸ | MERTK | Q12866 | 10/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26034086 | 0.92 | MET (0.70) | METAXLRIPK2RIPK1RIPK3 | |
| SCHEMBL26033156 | 0.89 | MET (0.71) | METAXLRIPK2RIPK1RIPK3 | |
| SCHEMBL25364883 | 0.88 | AXL (0.67) | METAXLTYRO3MERTKCYP3A4 | |
| SCHEMBL25366554 | 0.88 | MET (0.75) | METAXLTYRO3MERTKCYP3A4 | |
| SCHEMBL26033949 | 0.88 | AXL (0.67) | METAXLTYRO3MERTK | |
| SCHEMBL25365534 | 0.85 | MET (0.83) | METAXLRIPK2RIPK1RIPK3 | |
| SCHEMBL25366841 | 0.85 | MET (0.67) | METAXLRIPK2RIPK1RIPK3 | |
| SCHEMBL25367132 | 0.84 | MET (0.70) | METAXLRIPK2RIPK1RIPK3 | |
| SCHEMBL25366786 | 0.84 | MET (0.67) | METAXLRIPK2RIPK1RIPK3 | |
| SCHEMBL25366819 | 0.84 | MET (0.74) | METAXLRIPK2RIPK1RIPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023156864-A1 | PYRIDAZINONE-BASED COMPOUNDS AS AXL, C-MET, AND MER INHIBITORS AND METHODS OF USE THEREOF | CMG PHARMACEUTICAL CO., LTD. (KR) | 2023-08-24 | — | — | WO | disclosed |