Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16092908 | 0.79 | L3MBTL1 (0.47) | KDM4EALDH1A1TDP1L3MBTL1EPHX2 | |
| SCHEMBL26033101 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1TDP1NPSR1 | |
| SCHEMBL26031933 | 0.70 | ALDH1A1 (0.37) | KDM4EALDH1A1NPSR1 | |
| SCHEMBL10181124 | 0.70 | NPSR1 (0.42) | KDM4EEPHX2SMN1; SMN2NPSR1EPHX1 | |
| SCHEMBL20261888 | 0.70 | NPSR1 (0.42) | KDM4EEPHX2SMN1; SMN2NPSR1EPHX1 | |
| SCHEMBL25623301 | 0.70 | L3MBTL1 (0.47) | KDM4EALDH1A1TDP1L3MBTL1EPHX2 | |
| SCHEMBL26033458 | 0.67 | KDM4E (0.37) | KDM4E | |
| SCHEMBL2774793 | 0.67 | KDM4E (0.53) | KDM4EALDH1A1TDP1L3MBTL1EPHX2 | |
| SCHEMBL6533951 | 0.67 | KDM4E (0.53) | KDM4EALDH1A1TDP1L3MBTL1EPHX2 | |
| SCHEMBL3530758 | 0.67 | KDM4E (0.53) | KDM4EALDH1A1TDP1L3MBTL1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4230264-A2 | PRODRUGS OF FUMARATES AND THEIR USE IN TREATING VARIOUS DESEASES | Alkermes Pharma Ireland Limited (IE) | 2023-08-23 | — | — | EP | disclosed |