SCHEMBL2603375

SCHEMBL2603375

N#COc1ccc(C(c2ccc(N=C=O)cc2)(c2ccc(N=C=O)cc2)c2ccc(N=C=O)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TRPA1 O75762 1/20 0.32
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16545330 1.00 CYP3A4 (0.39) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL16186419 0.93 CYP3A4 (0.34) CYP3A4TSHRTRPA1
SCHEMBL34741 0.89 CYP3A4 (0.47) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL12908787 0.87 TSHR (0.37) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL25873141 0.87 CYP3A4 (0.37) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL13084705 0.86 CYP3A4 (0.36) CYP3A4TSHRMAPK1TDP1
SCHEMBL10033172 0.84 CYP3A4 (0.42) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL15981020 0.84 CYP3A4 (0.42) CYP3A4TSHRMAPK1TDP1TRPA1
SCHEMBL25873160 0.83 CYP3A4 (0.34) CYP3A4TSHRTRPA1
SCHEMBL25873163 0.83 CYP3A4 (0.34) CYP3A4TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9840701-B2 Porous membrane having immobilized enzyme, porous membrane composite including the same, and preparation method thereof GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-12-12 US disclosed
US-20170101660-A1 ENZYME-IMMOBILIZED POROUS MEMBRANE AND PREPARATION METHOD OF ANTIBIOTICS USING THE SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2017-04-13 US disclosed
US-20160348090-A1 POROUS MEMBRANE HAVING IMMOBILIZED ENZYME, POROUS MEMBRANE COMPOSITE INCLUDING THE SAME, AND PREPARATION METHOD THEREOF GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-12-01 US disclosed
US-20150099288-A1 POROUS MEMBRANE HAVING IMMOBILIZED ENZYME, POROUS MEMBRANE COMPOSITE INCLUDING THE SAME, AND PREPARATION METHOD THEREOF GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-09 US disclosed
US-20150059579-A1 GAS SEPARATION MEMBRANE FOR CARBON DIOXIDE AND PREPARATION METHOD THEREOF GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-03-05 US disclosed
US-8815967-B2 Porous polyurea material and methods for preparing the same Gwangju Institute of Science an Technology (KR) 2014-08-26 US disclosed
US-20120095123-A1 POROUS POLYUREA MATERIAL AND METHODS FOR PREPARING THE SAME GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170101660-A1 ENZYME-IMMOBILIZED POROUS MEMBRANE AND PREPARATION METHOD OF ANTIBIOTICS USING THE SAME ADA, ANPEP, PEPD CYP3A4 360/4885TSHR 2997/4885MAPK1 4231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.