Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TK1 | P04183 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26034728 | 0.89 | ASAH1 (0.38) | ASAH1METTK1ALDH1A1KDM4E | |
| SCHEMBL26039626 | 0.89 | ASAH1 (0.42) | ASAH1METUPP1HPGDTK1 | |
| SCHEMBL26034691 | 0.86 | TYMS (0.42) | HPGDALDH1A1TYMSDAOKDM4E | |
| SCHEMBL24205211 | 0.85 | CYP2C9 (0.46) | ASAH1TK1 | |
| SCHEMBL26034605 | 0.85 | CYP2C9 (0.46) | ASAH1TK1 | |
| SCHEMBL26035362 | 0.85 | CYP2C9 (0.46) | ASAH1TK1 | |
| SCHEMBL26034683 | 0.80 | MAPK1 (0.47) | HPGDTK1ALDH1A1MAPK1 | |
| SCHEMBL24205192 | 0.79 | ASAH1 (0.47) | ASAH1MET | |
| SCHEMBL7768621 | 0.79 | LMNA (0.52) | ASAH1KDM4E | |
| SCHEMBL26035406 | 0.78 | CA1 (0.41) | ASAH1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6A, PDE6D | ASAH1 1148/4885MET 4772/4885UPP1 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.