Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TK1 | P04183 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TYMP | P19971 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17583278 | 0.86 | TYMP (0.54) | MAPK1TK1HPGDTYMP | |
| SCHEMBL23897613 | 0.84 | MAPK1 (0.51) | MAPK1TK1HPGDTYMPALDH1A1 | |
| SCHEMBL7768621 | 0.84 | LMNA (0.52) | — | |
| SCHEMBL17583355 | 0.82 | TK1 (0.52) | TK1TYMP | |
| SCHEMBL26034665 | 0.81 | TK2 (0.53) | TK1TYMP | |
| SCHEMBL26034607 | 0.81 | TK2 (0.53) | TK1TYMP | |
| SCHEMBL26035299 | 0.81 | TK2 (0.53) | TK1TYMP | |
| SCHEMBL26034685 | 0.80 | ASAH1 (0.45) | MAPK1TK1HPGDALDH1A1 | |
| SCHEMBL5476039 | 0.78 | TK1 (0.67) | MAPK1TK1HPGDTYMP | |
| SCHEMBL26034691 | 0.77 | TYMS (0.42) | HPGDTYMPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6A, PDE6D | MAPK1 3072/4885TK1 2438/4885HPGD 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.