SCHEMBL26035192

SCHEMBL26035192

CCCCCCCCCCCCCCCC(=O)NCC(C)(C)COCC(C)(C)CNC(=O)[C@H](CCC(=O)NCC(C)(C)COC(C)(C)CNC(=O)CCCCCCCCCCCCCCC)NC(=O)CC(C)C

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.40
NOD1 Q9Y239 7/20 0.38
LPAR3 Q9UBY5 4/20 0.35
LPAR1 Q92633 2/20 0.35
MEN1 O00255 1/20 0.33
FAAH O00519 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26034975 0.82 GLP1R (0.37) GLP1RNOD1LPAR3LPAR1FAAH
SCHEMBL26034893 0.80 GLP1R (0.34) GLP1RNOD1LPAR3
SCHEMBL27143004 0.79 GLP1R (0.43) GLP1RNOD1LPAR3LPAR1
SCHEMBL26035269 0.79 GLP1R (0.35) GLP1RNOD1LPAR3
SCHEMBL27117452 0.79 GLP1R (0.42) GLP1RNOD1LPAR3LPAR1
SCHEMBL26034986 0.78 HRH3 (0.37) GLP1RLPAR1MEN1FAAHKMT2A
SCHEMBL25840094 0.75 GLP1R (0.36) GLP1RNOD1LPAR3LPAR1FAAH
SCHEMBL26036004 0.74 BIRC2 (0.39) GLP1RNOD1LPAR3FAAH
SCHEMBL26031954 0.73 GLP1R (0.63) GLP1RNOD1LPAR3LPAR1FAAH
SCHEMBL26031980 0.73 GLP1R (0.63) GLP1RNOD1LPAR3LPAR1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 GLP1R 1683/4885NOD1 4873/4885LPAR3 1763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.